R&D Initiatives

Advanced Technology Services

Set-up of the validation protocol and quality control of the splitters obtained from 3D printing in the CZFB facilities and co-designed by LEITAT. Dimensional, mechanical, emission and microbiological tests.
Set-up of the cleaning and sterilization protocol prior to the distribution of the splitters obtained by 3D printing and their effectiveness over time.
Set-up of the in-house protocol for the validation of masks manufactured specifically for the Covid-19 crisis, in collaboration with organizations such as AENOR.

Health & Biomedicine

Patients who have overcome SARS-Cov2 infection have developed immunity against the infection. The initiative promoted by Leitat-Salud in collaboration with other research centers (Taulí, CReSA) is based on cloning (duplicating) their immune system for the generation of antibody libraries and thus being able to select the best antibodies for therapy or diagnosis, in a period of less than 12 months.
Research in the development of a multiplex rapid diagnostic device for the determination of the immune response of patients against SARS-Cov2 combined with other infection-indicating proteins. This device will allow identifying patients at different stages of infection in just 15 minutes using a small blood sample. (in collaboration with the company Atrys)
Monoclonal antibodies are key elements for the therapy and diagnosis of most diseases. The Health Department has already started the process of generating antibodies to have these key tools for present and future needs against SARS-Cov2.
One of the side effects of those infected with COVID-19 is pulmonary fibrosis for which effective therapies are being sought. This development is being worked with the company Greenaltech.
The objective of this initiative is to develop another type of fast, reliable, cheap and effective Point-of-care diagnostic kit to detect SARS-Cov-2 viruses by detecting viral proteins using conjugated gold nanoparticles. Research is being carried out together with Endor Nanotechnologies and other companies.

Health & Biomedicine – Energy & Engineering

This technology has been developed within the framework of the European project ATTRACT (H2020-INFRAINNOV-2017, https://bit.ly/3dBloqr). PHIL technology will revolutionize the rapid molecular diagnostics sector by reducing the specific detection limit of SARS-CoV-2 without the need for DNA amplification and with a testing time of less than 5 minutes.
This development is a re-orientation of an ongoing project (PHIL, Attractant call) in collaboration with IFAE. Parc Taulí has joined the proposal.

Energy & Engineering

Applied Chemistry & Materials

The main technological innovation of this project is based, on the one hand, on the development of broad-spectrum surface decontamination solutions that will focus not only on bacteria and fungi, but also on viruses (including the SARS-CoV-2 coronavirus), which will help to considerably reduce the concentration of microorganisms harmful to human health on common surfaces in both the domestic and hospital environment. On the other hand, highly durable solutions (of more than 24 hours) will be investigated so that the number of operations of cleaning personnel can be reduced, while reducing their own risk of microbiological contamination. Leitat has experience in preliminary studies of surface cleaners and antimicrobial surfaces for applications related to the domestic and aeronautical sectors, technical fabrics, drinking water and greywater networks, and household appliances.
The development of this project involves the incorporation of nanofibers into the filter layer that will provide an improvement in the filtering capabilities and efficiency of the face masks, as well as a longer life span or lower cost, in addition to providing them with biocidal and antiviral activity due to doping of the Nanofiber surface. Preliminary studies carried out at Leitat have shown that these filter materials can show FFP2-FFP3 filtration efficiencies.

Circular Economy

Through this technique we can characterize the virus genetics in depth to study its evolution, reconstruct the transmission chains or study the presence of characteristics related to the different degrees of severity that infected patients show.
Surfaces contaminated with the virus are a vehicle for the transmission of COVID-19 disease. The main objective of these studies is to determine for how long the virus infectivity is maintained on different types of surfaces and to study if the tissues (clothing, sanitary uniforms, etc.) can act as transmission vehicles. This is of particular interest in the hospital setting, where hundreds of patients are being cared for and treated every day. (A development of LEITAT + CRESA * + Clinical partner)
Application of technologies such as UV, Plasma, Ozone, electrochemical technology, among others.